By improving diagnostic accuracy, deep-learning-aided MRI-based diagnosis could be critical in implementing early interventions for ADHD patients. Approximately 5% of American pre-school and school-aged children have been diagnosed with ADHD. These children and adolescents face a high risk of failing in academic study and building social relationships, which can result in financial hardship for families and create a tremendous burden on society.
The approach also has potential beyond ADHD, according to Dr. He.
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"This model can be generalized to other neurological deficiencies," she said. "We already use it to predict cognitive deficiency in pre-term infants. We scan them soon after birth to predict neurodevelopmental outcomes at two years of age."
In the future, the researchers expect to see the deep learning model improve as it is exposed to larger neuroimaging datasets. They also hope to better understand the specific breakdowns or disruptions in the connectome identified by the model that are associated with ADHD.
"A Multichannel Deep Neural Network Model Analyzing Multiscale Functional Brain Connectome Data for Attention Deficit Hyperactivity Disorder Detection." Collaborating with Dr. He were Ming Chen, B.S., Hailong Li, Ph.D., Jinghua Wang, Ph.D., Jonathan R. Dillman, M.D., M.Sc., and Nehal A. Parikh, D.O., M.S.
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