In attempting to realize its objective, the SonoDrugs project will take a two-pronged approach: the first is based on magnetic resonance imaging (MRI) guidance and the second is based on ultrasound guidance. The project's research on MRI-guided drug delivery will largely be targeted at potential treatments for cancer. The SonoDrugs project aims to develop MRI techniques to simultaneously image the patient's anatomy, detect the arrival of MRI-labeled drug-loaded particles at the disease site, measure the local heating effect of the ultrasound pulses, and monitor the temperature triggered release of drugs from the particles.
For potential applications in the treatment of cardiovascular disease, the project will focus on the use of ultrasound as the primary imaging modality as well as the means of releasing drugs from pressure sensitive microbubbles. Philips Research is at the forefront of research into the drug delivery potential of microbubbles by adapting existing microbubble technology so that microbubbles can deliver precise doses of drugs exactly where they might be needed in the body.
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Read DOTmed's exclusive report on microbubbles:
https://www.dotmed.com/news/story/7152/
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