FRANKFURT, Germany, Jan. 13, 2020 /PRNewswire/ -- The Journal of Electrocardiology has published a study showing unparalleled accuracy in non-invasive coronary artery disease (CAD) detection using Cardisio's new low-cost method which involves no radiation exposure.
The study demonstrates a sensitivity of over 97% in male patients and over 90% in female patients, and specificity of over 74% and over 76%, respectively.
Cardisiography is a new, unique testing method developed by the European startup Cardisio that delivers highly precise results within just a few minutes. It is a non-invasive, independent, repeatable, fast, and cost-effective method of detecting CAD in the resting heart. It offers a complementary and more effective alternative to traditional procedures such as stress ECG and echocardiography for early identification of heart disease without radiation exposure.
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People with coronary artery disease are frequently symptom-free until the onset of a severe event such as a heart attack. Because the Cardisiography test is highly accurate, low-cost and easy to administer, it has the potential to detect CAD earlier, helping patients receive the right pharmacological or other treatment before a potentially fatal heart attack.
"We see great potential in Cardisiography for early detection of symptom-free people with coronary artery disease. Broad-scale early detection has not been possible until now," said Sotirios Spiliopoulos, M.D. Ph.D., Department of Geriatrics, St. Vinzenz-Hospital, Dinslaken, one of the authors of the study.
Cardisio's system consists of two integrated components: the CardisioGraph, a device that records three-dimensional electric currents via five electrodes attached to the thorax, and the CardisioCloud, an Artificial Intelligence (AI) software application that uses multiple algorithms and machine learning methods to evaluate the measurements. The CardisioGraph collects data from the resting heart for approximately four minutes, and the Cardisiography result, along with a supplementary standard ECG report, are available about one minute later.
In the published study, researchers examined 595 patients who had been admitted to several medical centers in Germany for a coronary angiogram, the current gold standard CAD examination. Cardisiography results were compared to results yielded by the angiogram tests.
Following completion of the study referenced above, Cardisio has made improvements to its algorithms that have increased the specificity significantly, along with a slight increase in sensitivity in both males and females.