"We are very pleased to enter into this license agreement with Blue Earth Diagnostics, as their experience in the successful rapid development, approval and commercialization of Axumin will accelerate this first class of exciting "rh" technology based agents towards routine clinical use worldwide," said Prof. Hans-Jürgen Wester, PhD, Founder of Scintomics and Chair, for Pharmaceutical Radiochemistry at the Technical University of Munich (TUM), Germany. "Our early clinical experience with 18F-rhPSMA-7 has been very encouraging and justifies advancing an "rh" candidate into formal clinical development," added Matthias Eiber, MD, attending physician at the Department of Nuclear Medicine, Klinikum rechts der Isar, TUM.

"As evidenced by its recent inclusion in the National Comprehensive Cancer Network® guidelines, 18F-fluciclovine has become established as a standard-of-care PET imaging agent in the United States for men with recurrent prostate cancer," said Judd Moul, MD, Professor of Surgery and Director, Duke Prostate Center, Duke University Medical Center, Durham, NC. "It is clear that PSMA-targeted PET imaging agents will play an important role in the future management of prostate cancer patients. However, there is a wide array of these agents in development, and some have more promising attributes than others. Optimally, a PSMA-targeted diagnostic agent for routine clinical use should be labeled with the radioisotope 18F for its durability and possess favorable clinical attributes that facilitate broad applicability and utility in men with prostate cancer."

About rhPSMA
rhPSMA was invented by Hans-J Wester and Alexander Wurzer at the Department of Pharmaceutical Radiochemistry of the Technical University of Munich, Germany, where it has been utilized clinically under German legislation by Matthias Eiber at the Department of Nuclear Medicine for the diagnostic imaging of men with both primary and recurrent prostate cancer. Bayerische Patentallianz (BayPAT), the technology transfer office of Bavarian Universities and Universities of Applied Sciences out-licensed the Radiohybrid ("rh") PSMA-targeted technology to Scintomics in 2017. 18F rhPSMA consists of a prostate-specific membrane antigen (PSMA) receptor ligand, which attaches to and is internalized by prostate cancer cells, and is labeled with the 18F radioisotope for PET imaging. rhPSMA compounds can also be labeled with the radioisotope 177Lu for therapeutic use. 18F rhPSMA and 177Lu rhPSMA have not received regulatory approval.

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