DOTmed Home MRI Oncology Ultrasound Molecular Imaging X-Ray Cardiology Health IT Business Affairs
News Home Parts & Service Operating Room CT Women's Health Proton Therapy Endoscopy HTMs Mobile Imaging
Endroit courant :
> This Story

Ouverture ou Registre to rate this News Story
Forward Printable StoryPrint Comment




Business Affairs Homepage

Varian acquires Noona Healthcare Gains mobile service app that captures PROs

Philly leads US cities in need of radiologists Shortages continue to leave radiologists in high demand

Siemens Healthineers holds grand opening of new Erlangen HQ Continuing its 140 year presence in the city

Does GE CEO move cast doubt on healthcare spinoff? Industry analysts weigh in on how this could change the game plan

Healthcare has a serious problem with wasted spending How supply chain can hold the key to more efficient hospital finances

Mass imaging exam cancellations by VA puts veterans lives at risk Medically needed scans reportedly removed from schedule to reduce backlog

Hologic to acquire Focal Therapeutics for $125 million Furthering its expansion into the breast conservation surgery market

GE CEO Flannery is out as Culp Jr. named chairman and CEO The latest shake-up in a year full of transitions

China tariffs now hit $4.7 billion worth of U.S. medical devices AdvaMed warns that things could get worse before they get better

Samsung in talks with Nipro for medical device division sale May sharpen focus on diagnostic imaging solutions

Jason Reed
Courtesy of John Wallace
at VCU Massey Cancer

Scientists develop new imaging technique that could map DNA mutations

par Lauren Dubinsky , Senior Reporter
Scientists at Virginia Commonwealth University developed a new imaging technique that may be able to map DNA mutations and transform the way certain diseases are diagnosed and treated.

The technique combines high-speed atomic force microscopy and chemical bar coding to map DNA almost as accurately as DNA sequencing.

Story Continues Below Advertisement

Dunlee announces the relaunch of DA135 CT/e, DA165NP and Akron tubes

Dunlee announces the return of the DA135 CT/e, DA165NP, S532B and S532Q(known as the Akron tubes) CT Replacement tubes, making its full portfolio of CT tubes for GE and Siemens CT scanners available once again.Click to learn more

"Current 'genomic medicine' is not widely available in community hospitals and other non-urban settings," Jason Reed, physicist at the university, told HCB News. "The unfortunate fact is that patients from rural areas, or those from lower income groups without access to the most recent molecular methods, will not receive the best available diagnostics."

Biomedical imaging techniques like fluorescence in situ hybridization can evaluate DNA at a resolution of several hundred thousand base pairs, but the new technique can map DNA to a resolution of tens of base pairs while also creating images up to a million base pairs in size.

The chemical bar coding application leverages an enzyme called CRISPR that was programmed to cut DNA at precise locations that the cell can repair on its own. The team changed the chemical reaction conditions of the enzyme so it only sticks to the DNA and doesn’t actually cut it.

CRISPR is ideal for the bar coding application because it’s physically bigger than the DNA molecule and 90 percent efficient at bonding to it. Since it’s easy to see CRISPR enzymes, genetic mutations can be seen among the patterns in DNA.

In a study published on Tuesday in Nature Communications, the team of scientists mapped genetic translocations present in lymph node biopsies of lymphoma patients. The translocations occur when one section of DNA is copied and pasted to the wrong place in the genome, and they are particularly common in blood cancers like lymphoma.

There are many uses for this new imaging technique, but the team has chosen to focus on medical applications. They are currently developing software based on existing algorithms that can assess patterns in sections of DNA up to and over a million base pairs in size.

They hope this will translate into a shoebox-sized machine for pathology labs that assists with diagnosing and treating diseases linked to genetic mutations.

Business Affairs Homepage

You Must Be Logged In To Post A Comment

Développez la notoriété de votre marque
Enchères + Ventes Privées
Obtenir le meilleur prix
Acheter des équipement / pièces
Trouver le meilleur prix
Infos du jour
Lire Les dernières nouvelles
Consulter tous les utilisateurs DOTmed
Éthique concernant DOTmed
Voir notre programme d'éthique
L'or partie le programme de fournisseur
Recevoir des demandes PH
Programme de marchand de service d'or
Recevoir des demandes
Fournisseurs de soins de santé
Voir tous les outils des HCP (abréviation pour les professionnels de la santé)
Les travaux/Formation
Trouver / combler un poste
Parts Hunter +EasyPay
Obtenir des devis de pièces
Certification Récentes
Voir les utilisateurs récemment certifiés
Evaluation Récentes
Voir les utilisateurs récemment certifiés
Central de location
Louer de l’équipement à moindre prix
Vendre des équipements / pièces
Obtenir le maximum d'argent
Service le forum de techniciens
Trouver de l'aide et des conseils
Simple demande de propositions
Obtenir des devis pour des appareils
Expo Virtuelle
Trouver des services d'appareils
L'Access et l'utilisation de cet emplacement est sujet aux modalités et aux conditions du notre de nos MENTIONS LEGALES & DONNEES PERSONELLES
Propriété de et classe des propriétaires DOTmedà .com, inc. Copyright ©2001-2018, Inc.