Following an extensive national search, Cleveland Clinic has appointed Brian Rubin, M.D., Ph.D., as chair of the Robert J. Tomsich Pathology & Laboratory Medicine Institute (RT-PLMI).
In this role, Dr. Rubin will oversee 1,500 caregivers and 100 pathologists who process more than 19 million tests annually, touching virtually every Cleveland Clinic patient and thousands of others around the world.
Dr. Rubin joined Cleveland Clinic in 2006. Prior to this appointment, he served as vice-chair of research and director of soft tissue pathology at RT-PLMI. He also is professor of Pathology at Cleveland Clinic Lerner College of Medicine.

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Dr. Rubin’s career has been dedicated to better understanding the diagnosis and classification of soft tissue neoplasms, especially sarcomas, where he is a prominent national and international figure. He is widely regarded as a thought leader in the field and is a founding member of the International Society of Bone and Soft Tissue Pathology. His laboratory focuses on understanding the pathogenesis of sarcomas with the major aim of developing targeted therapies.
“Brian is an exceptional leader who is committed to quality, mentoring and program development,” said Cleveland Clinic Chief of Staff Herbert Wiedemann, M.D. “He brings a wealth of knowledge, expertise and understanding to this position.”
Dr. Rubin also will be responsible for overseeing the institute’s academic and research mission. RT-PLMI is an active teaching center with 28 residents as well as fellowships in nine specialty areas.
“It is a privilege to be given the opportunity to lead our extraordinary group of caregivers,” Dr. Rubin said. “I look forward to working together to continue to improve quality, safety and the patient experience.”
Dr. Rubin earned his Ph.D. in molecular biology and M.D. from Cornell University Medical College. He completed residency training in anatomic pathology and a fellowship in soft tissue/bone pathology and cancer genetics at Brigham and Women’s Hospital.
Dr. Rubin succeeds Robert Wyllie, M.D., Chief Medical Operations Officer, who served as interim chair of RT-PLMI since September 2016.