Dutch physiologist
Willem Einthoven
Willem Einthoven
This Month in Medical History - March: The Heart of the Matter
March 18, 2009
by Sean Ruck, Contributing Editor
This report originally appeared in the March 2009 issue of DOTmed Business News
On March 22nd, 1905, Dutch physiologist Willem Einthoven used telephone communications networks to transmit something a bit different than the usual conversation. In fact, it's doubtful there were many people alive at the time that could have made heads or tails of the message being sent. You see, on that date, Einthoven brought his research to a culmination by transmitting and recording the first telecardiogram.
The experiment and trials had begun earlier in the year when Einthoven transmitted electrocardiograms between a hospital and his lab by phone line over a distance of about one mile.
By the time Einthoven had begun to make a name, electrocardiograms (ECGs or sometimes EKGs) had been around for nearly a century. However, the early ECGs were impractical as the equipment wasn't sensitive enough to register electrical discharges from the heart.
Einthoven built upon the research of physiologist Augustus Desire Waller, who in 1887 was able to register the current of the heart as deduced from the body surface by using a capillary electrometer. Einthoven watched Waller demonstrate the feat during the First International Congress of Physiologists two years later. He was able to repeat the experiment on his own and further refine the technique.
In 1895, Einthoven was able to use the capillary electrometer to record graphic reproductions of the variations of the electric charges caused by the contractions of the heart. Einthoven defined the physical constants of the capillary electrometer and calculated the true curve, which he called the electrocardiogram.
In 1901, Einthoven invented a new galvanometer to produce electrocardiograms using a fine quartz string coated in silver. His "string galvanometer" weighed 600 pounds. A similar machine was constructed earlier by Clement Ader but the lower sensitivity of Ader's machine was considerable and hobbled its usefulness.
The following year Einthoven published the first electrocardiogram recorded on a string galvanometer. The string galvanometer is also known by a different name - "Einthoven's Galvanometer."
Although his work up to that point had far-surpassed most of his peers, Einthoven continued to create innovations and unearth more discoveries about the heart. In 1912, his research on the explanation of the respiratory changes in the electrocardiogram led him to the scheme of the equilateral triangle, considering the extremities as elongations of the electrodes. The information received from the contacts thus represents the projection of what takes place in the heart. With simultaneous registration of the three contacts, the size and direction of the resultant of all potential differences in the heart could be calculated minute by minute. Clinical electrocardiograms were studied by connecting heart patients in the academic hospital to the instrument in Einthoven's laboratory by means of a cable.
Einthoven's Triangle is an imaginary equilateral triangle mapped out over a body. The heart rests at the center of the triangle and the three standard limb leads of the electrocardiogram represent the points of the triangle.
Einthoven's Law is based on the information gathered from the Triangle. It states that in an electrocardiogram at any given instant, the potential of any wave in lead two is equal to the sum of the potentials in lead one and three. It may not be as earth-shattering as Einstein's theories - but for the medical world, it probably came close.
He was duly recognized for his major contributions and in 1924, Einthoven was awarded the Nobel Prize for physiology or medicine for his discovery of the mechanism of the electrocardiogram. Being an incredibly modest man by the estimations of his peers, it's questionable if he would admit to the importance of his work and his discoveries. His goal was clear though, to serve mankind.
"We should first endeavor to better understand the working of the heart in all its details, and the cause of a large variety of abnormalities. This will enable us, in a possibly still-distant future and based upon a clear insight and improved knowledge, to give relief to the suffering of our patients." - Willem Einthoven (1860-1927)
On March 22nd, 1905, Dutch physiologist Willem Einthoven used telephone communications networks to transmit something a bit different than the usual conversation. In fact, it's doubtful there were many people alive at the time that could have made heads or tails of the message being sent. You see, on that date, Einthoven brought his research to a culmination by transmitting and recording the first telecardiogram.
The experiment and trials had begun earlier in the year when Einthoven transmitted electrocardiograms between a hospital and his lab by phone line over a distance of about one mile.
By the time Einthoven had begun to make a name, electrocardiograms (ECGs or sometimes EKGs) had been around for nearly a century. However, the early ECGs were impractical as the equipment wasn't sensitive enough to register electrical discharges from the heart.
Einthoven built upon the research of physiologist Augustus Desire Waller, who in 1887 was able to register the current of the heart as deduced from the body surface by using a capillary electrometer. Einthoven watched Waller demonstrate the feat during the First International Congress of Physiologists two years later. He was able to repeat the experiment on his own and further refine the technique.
In 1895, Einthoven was able to use the capillary electrometer to record graphic reproductions of the variations of the electric charges caused by the contractions of the heart. Einthoven defined the physical constants of the capillary electrometer and calculated the true curve, which he called the electrocardiogram.
In 1901, Einthoven invented a new galvanometer to produce electrocardiograms using a fine quartz string coated in silver. His "string galvanometer" weighed 600 pounds. A similar machine was constructed earlier by Clement Ader but the lower sensitivity of Ader's machine was considerable and hobbled its usefulness.
The following year Einthoven published the first electrocardiogram recorded on a string galvanometer. The string galvanometer is also known by a different name - "Einthoven's Galvanometer."
Although his work up to that point had far-surpassed most of his peers, Einthoven continued to create innovations and unearth more discoveries about the heart. In 1912, his research on the explanation of the respiratory changes in the electrocardiogram led him to the scheme of the equilateral triangle, considering the extremities as elongations of the electrodes. The information received from the contacts thus represents the projection of what takes place in the heart. With simultaneous registration of the three contacts, the size and direction of the resultant of all potential differences in the heart could be calculated minute by minute. Clinical electrocardiograms were studied by connecting heart patients in the academic hospital to the instrument in Einthoven's laboratory by means of a cable.
Einthoven's Triangle is an imaginary equilateral triangle mapped out over a body. The heart rests at the center of the triangle and the three standard limb leads of the electrocardiogram represent the points of the triangle.
Einthoven's Law is based on the information gathered from the Triangle. It states that in an electrocardiogram at any given instant, the potential of any wave in lead two is equal to the sum of the potentials in lead one and three. It may not be as earth-shattering as Einstein's theories - but for the medical world, it probably came close.
He was duly recognized for his major contributions and in 1924, Einthoven was awarded the Nobel Prize for physiology or medicine for his discovery of the mechanism of the electrocardiogram. Being an incredibly modest man by the estimations of his peers, it's questionable if he would admit to the importance of his work and his discoveries. His goal was clear though, to serve mankind.
"We should first endeavor to better understand the working of the heart in all its details, and the cause of a large variety of abnormalities. This will enable us, in a possibly still-distant future and based upon a clear insight and improved knowledge, to give relief to the suffering of our patients." - Willem Einthoven (1860-1927)